Multifocal fixed drug eruption with COX-2 inhibitor-celecoxib
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چکیده
منابع مشابه
Multifocal fixed drug eruption due to ornidazole
Case report A 40-year old woman applied to the Immunology and Allergy clinic with pruritic erythematous lesions over the lateral sides of both arms and right hip within 30 minutes after the ingestion of ornizadole 500 mg tablet. She reported that five recurrent reactions emerged with the same drug on the same locations previously, and their severity was increased consecutively. She was prescrib...
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In addition to the well-established pathophysiological role that COX-2 plays in inflammation, recent evidence implies that this isoform may also be involved in multiple biologic events throughout the tumorigenic process. Many epidemiological studies demonstrate that nonsteroidal anti-inflammatory drugs (NSAIDs) reduce the risk of a wide range of tumors. Further, COX-2 is chronically overexpress...
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TNPM presents as subcorneal or intraepidermal pustules composed mainly of neutrophils; this finding helps to differentiate TNPM from NTE, in which there is a predominance of eosinophils. In conclusion, we must be aware that TNPM is a benign condition with no systemic manifestations and it does not require treatment. This entity can be confused with serious infections, and patients with TNPM may...
متن کاملMultifocal fixed drug eruption probably induced by mefenamic acid.
TNPM presents as subcorneal or intraepidermal pustules composed mainly of neutrophils; this finding helps to differentiate TNPM from NTE, in which there is a predominance of eosinophils. In conclusion, we must be aware that TNPM is a benign condition with no systemic manifestations and it does not require treatment. This entity can be confused with serious infections, and patients with TNPM may...
متن کاملFirst multifocal bullous fixed drug eruption due to etodolac.
Fixed drug eruption (FDE) usually appears as a solitary/small number of pruritic, well circumscribed, erythematous--violaceous macules that evolve into oedematous plaques which typically resolve after the discontinuation of the offending drug, leaving residual hyperpigmentation. This eruption is considered pathognomonic of a drug-induced dermatosis and is triggered within a few minutes or up to...
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology
سال: 2013
ISSN: 0019-5154
DOI: 10.4103/0019-5154.108057